A native of York, she was a close friend of Sarah Crosby and an aspiring preacher about whom John Wesley expressed reservations. There is some uncertainty over her identity, but it appears that she was the daughter of Ebenezer Harrison of York, rather than the wife of Lancelot Harrison, and was a well-educated middle class lady. She lost her sight at 13, but recovered it later. Converted c.1750 under Jonathan Maskew, she became a leading member of the York society. In 1768 she proved herself to be a peace-maker at a time of anti-Methodist rioting in Beverley. John Atlay was converted under her preaching. Later she moved to London, where she died on 19 December 1801. Joseph Benson preached her funeral sermon.