The first British lay medical missionary. He was educated at Wesley College (now Queen's College), Taunton and King's College, London and appointed to China. He arrived in Hankow (Hankou) in May 1864 and began medical work with Josiah Coxas interpreter. In 1866 he built a hospital in Hankow (the 'Hospital of Universal Love'), the first in Central China, and also opened a dispensary in Wuchang. He returned home in December 1870, weakened in health and was unable to offer for a second term of service. He died on 29 March 1888 from taking poison during a bout of depression due to overwork.